It’s time to take out a new lease on Life.

Find out how one of the many rapid onset antidepressant treatments (including, but not limited to intravenous Ketamine) at the Canadian Rapid Treatment Center of Excellence can change your life today.
1100 Dundas St W, Unit #6, L5C 4E7   |   Mississauga, Ontario   |   1-416-943-6284 
The Canadian Rapid Treatment Center of Excellence is currently recruiting participants to take part in a clinical trial evaluating the safety and efficacy of psilocybin (the psychedelic identified in magic mushrooms) for depression. To learn more about the trial, please visit the study sponsor’s website. If you are interested in participating, please email our research coordinator Nelson Rodrigues at nelson.rodrigues@crtce.com.

About the CRTCE

The CRTCE’s Intravenous Ketamine Infusion Therapy aims to aid those suffering from several treatment-resistant conditions. Our clinic provides a comfortable environment focused on the safety and success of each individual patient.

Learn More About Ketamine Treatment

Understanding Intravenous Ketamine Infusion Therapy

How Intravenous Ketamine Infusion Therapy Works

Research & Clinical Studies

Refer a Patient

Meet Our Director

Dr. Roger McIntyre, M.D. FRCPC

Dr. Roger McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto and Head of the Mood Disorders Psychopharmacology Unit at the University Health Network, Toronto, Canada. Dr. McIntyre is also Executive Director of the Brain and Cognition Discovery Foundation (BCDF) in Toronto, Canada. Dr. McIntyre is also Director for the Depression and Bipolar Support Alliance (DBSA) from Chicago, Illinois, USA. Dr. McIntyre is also Professor and Nanshan Scholar at Guangzhou Medical University, and Adjunct Professor College of Medicine at Korea University.

Dr. McIntyre is also Clinical Professor State University of New York (SUNY) Upstate Medical University, Syracuse, New York, USA and Clinical Professor Department of Psychiatry and Neurosciences University of California School of Medicine, Riverside, California, USA.  Dr. McIntyre was named by Clarivate Analytics/Thomson Reuters in 2014, 2015, 2016, 2017 and 2018 as one of “The World’s Most Influential Scientific Minds”…

See Dr. McIntyre’s Full Bio

Top Academic Publisher

Dr. Roger McIntyre is also one of the most cited academics in psychiatry; you can be assured you are in capable hands during your visit at the Canadian Rapid Treatment Center of Excellence.

Dr. McIntyre’s Depression Research
Dr. McIntyre’s Bipolar Disorder Research

Media Coverage

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Is ketamine safe?2018-06-27T14:41:25+00:00

Ketamine has been used for many years in anesthesia and other medical conditions (e.g. pain disorders). The U.S. FDA approved ketamine in 1970 as an agent for anesthesia. During the last two decades, a growing body of evidence supports its use in treatment resistant mood disorders. When ketamine is administered at a center where the personnel are experts in the delivery of ketamine and where that center has appropriate safety monitoring and surveillance of patients, ketamine appears to be safe and generally well-tolerated. As ketamine has not been studied in mood disorders for longer periods of time (i.e. a year or longer), its long-term safety remains to be established, and it is currently a focus of research.

How long does it take before ketamine begins to work? How many infusions do I need?2018-06-27T14:50:00+00:00

Based on the available evidence, individuals receiving ketamine begin to report relief of depression within one day of administration of the first infusion. Others may take longer but overall the majority of people who are going to benefit from ketamine benefit from 1-2 weeks.

For what psychiatric disorders is ketamine best proven to be effective for?2018-06-27T14:40:18+00:00

Intravenous ketamine is a drug that has abuse liability. That being said, the doses of ketamine that are being used for the treatment of mood disorders are a relatively small dose. Moreover, there is no evidence those individuals receiving ketamine for treatment resistant mood disorders in carefully supervised and specialized centers are at risk of abusing ketamine and other substances, as a consequence of ketamine treatment (e.g. opiates).

How does ketamine work?2018-06-27T14:39:59+00:00

The mechanism of how ketamine alleviates depressive symptoms is not known. It is generally agreed that there are multiple mechanisms that likely contribute to ketamine’s ability to relieve depressive symptoms. It is hypothesized that these mechanisms include, but are not limited to, targeting glutamate, dopamine, serotonin, opiates, as well as molecules in the brain responsible for brain cell growth and development.

What is ketamine?2018-06-27T14:39:47+00:00

Ketamine is a pharmaceutical that was originally developed for the purpose of assisting in anesthesia. It is referred to as a dissociative anesthetic. The term dissociative anesthetic has more than one definition. One of the most commonly referred to definitions for a dissociative anesthetic is an agent that can cause dissociative symptoms, which loosely means that “reality can be somewhat blurred”. In other words, images may appear unreal or slightly distorted and/or create other perceptual disturbances.

How can I be assessed for eligibility for ketamine therapy?2018-06-27T14:51:57+00:00

A referral can be made by your healthcare provider at our referral page. Staff at the CRTCE will conduct a comprehensive assessment of your psychiatric history, medical history and family history. Moreover, a full list of all previous treatments taken will need to be determined to ensure you have a treatment resistant disorder. Once you have been determined to be eligible for ketamine therapy, an appointment time will be scheduled for you at the Canadian Rapid Treatment Center of Excellence (CRTCE).

Will my insurance company cover my treatment?2018-06-15T18:37:34+00:00

You’ll need to speak to your insurance company regarding the matter. These decisions are made on a case by case basis, as the use of ketamine in treating mood disorders is relatively new avenue of care.

Is ketamine treatment for depression paid for by the public health plan of Ontario (i.e. Ontario Health Insurance Plan, OHIP)?2018-05-31T16:29:32+00:00


How much does an acute treatment trial of ketamine cost at the Canadian Rapid Treatment Center of Excellence (CRTCE)?2018-09-25T10:44:15+00:00

The cost of an acute treatment trial (i.e. 4 infusions in two weeks) is $3000. This price includes the harmonized sales tax (HST). This fee represents the cost of professional services and the administration of this treatment. All individuals will need to pay the full cost of an acute treatment trial prior to having a first infusion schedule.

Who can make the referral and how can they make the referral?2018-06-27T14:52:49+00:00

Any one of your doctors may be able to submit a referral for an assessment to our clinic. To submit a referral, your doctor can visit www.crtce.com/refer-a-patient

How long do the infusions take and how long do I need to stay at the clinic?2018-06-27T14:45:02+00:00

Based on the available evidence, individuals receiving ketamine begin to report relief of depression within one day of administration of the first infusion. Others may take longer but the overall majority of people who are going to benefit from ketamine benefit within 1-2 weeks.

I found a new sense of hope.

When I found CRTCE Ketamine Infusion Therapy, and began to research the treatment, I felt my spirits lift. I felt hope. From the moment I contacted their office, I knew I was in good hands. As someone who works in healthcare, I couldn’t believe how kind and attentive Dr. McIntyre and his entire staff were. Thank you.

34 Year Old Woman

Contact Us

1100 Dundas St W, Unit #6,  L5C 4E7.
Mississauga, ON, Canada
Clinic Phone: 416-430-9619
Pharmacy Phone: 416-943-6284

Please remember, all individuals must be referred to CRTCE by their doctor prior to visiting our clinic. To be referred, please ask your doctor to send a referral for an initial assessment on our refer a patient page.