1100 Dundas St W, Unit #6, L5C 4E7 | Mississauga, Ontario | 1-416-430-9619
In light of COVID-19 the CRTCE will remain open while taking all the precautionary measures to ensure the safety of our patients and staff.
About the CRTCE
The CRTCE’s Intravenous Ketamine Infusion Therapy aims to aid those suffering from several treatment-resistant conditions. Our clinic provides a comfortable environment focused on the safety and success of each individual patient.
Ketamine has been used for many years in anesthesia and other medical conditions (e.g. pain disorders). The U.S. FDA approved ketamine in 1970 as an agent for anesthesia. During the last two decades, a growing body of evidence supports its use in treatment resistant mood disorders. When ketamine is administered at a center where the personnel are experts in the delivery of ketamine and where that center has appropriate safety monitoring and surveillance of patients, ketamine appears to be safe and generally well-tolerated. As ketamine has not been studied in mood disorders for longer periods of time (i.e. a year or longer), its long-term safety remains to be established, and it is currently a focus of research.
How long does it take before ketamine begins to work? How many infusions do I need?admin2018-06-27T14:50:00+00:00
Based on the available evidence, individuals receiving ketamine begin to report relief of depression within one day of administration of the first infusion. Others may take longer but overall the majority of people who are going to benefit from ketamine benefit from 1-2 weeks.
For what psychiatric disorders is ketamine best proven to be effective for?admin2018-06-27T14:40:18+00:00
Intravenous ketamine is a drug that has abuse liability. That being said, the doses of ketamine that are being used for the treatment of mood disorders are a relatively small dose. Moreover, there is no evidence those individuals receiving ketamine for treatment resistant mood disorders in carefully supervised and specialized centers are at risk of abusing ketamine and other substances, as a consequence of ketamine treatment (e.g. opiates).
How does ketamine work?admin2018-06-27T14:39:59+00:00
The mechanism of how ketamine alleviates depressive symptoms is not known. It is generally agreed that there are multiple mechanisms that likely contribute to ketamine’s ability to relieve depressive symptoms. It is hypothesized that these mechanisms include, but are not limited to, targeting glutamate, dopamine, serotonin, opiates, as well as molecules in the brain responsible for brain cell growth and development.
Ketamine is a pharmaceutical that was originally developed for the purpose of assisting in anesthesia. It is referred to as a dissociative anesthetic. The term dissociative anesthetic has more than one definition. One of the most commonly referred to definitions for a dissociative anesthetic is an agent that can cause dissociative symptoms, which loosely means that “reality can be somewhat blurred”. In other words, images may appear unreal or slightly distorted and/or create other perceptual disturbances.
How can I be assessed for eligibility for ketamine therapy?admin2018-06-27T14:51:57+00:00
A referral can be made by your healthcare provider at our referral page. Staff at the CRTCE will conduct a comprehensive assessment of your psychiatric history, medical history and family history. Moreover, a full list of all previous treatments taken will need to be determined to ensure you have a treatment resistant disorder. Once you have been determined to be eligible for ketamine therapy, an appointment time will be scheduled for you at the Canadian Rapid Treatment Center of Excellence (CRTCE).
Will my insurance company cover my treatment?admin2018-06-15T18:37:34+00:00
You’ll need to speak to your insurance company regarding the matter. These decisions are made on a case by case basis, as the use of ketamine in treating mood disorders is relatively new avenue of care.
Is ketamine treatment for depression paid for by the public health plan of Ontario (i.e. Ontario Health Insurance Plan, OHIP)?admin2018-05-31T16:29:32+00:00
Based on the available evidence, individuals receiving ketamine begin to report relief of depression within one day of administration of the first infusion. Others may take longer but the overall majority of people who are going to benefit from ketamine benefit within 1-2 weeks.